Pao Pereira is a domestic plant of South America and its tree has been residing in the Amazon rainforest for many centuries. Due to its curative features, this plant has been used as a traditional cure for a number of diseases for more than three centuries. Various publications in South America, North America, and Europe have already reviewed its medicinal properties like antiviral, anti-inflammatory, anticancer and highlighted its significance in the field of traditional medicine. The tree is also world-famous by other names i.e, Triguaaba, Pinguaciba, Poirier du Brésil, Geissospermumvellosii, Bergibita, Pau Pereira, and its bark is used to manufacture therapeutics drugs for many health disorders. In 1895, it was discovered in a study that the Pao has anti-fever characteristics and it is most effective for curing infrequent fevers. The anti-peristaltic, pain killer, anti-inflammatory, and antiviral activity of the Pao Pereira extract made up of bark of Pao tree, makes it usable in the treatment of Malaria, Fever, Constipation, Digestive disorder, Cancer, Liver diseases, Sexual disorder, and various health problems.
In 1878, John Miers, who was a botanist, in his scientific research discovered that Pao Pereira belongs to the Apocynaceae family. The Pao Pereira extracts have been found useful in the treatment of cancer. The anti-cancer attribute of plant extracts stops the growth of cancer cells without affecting the healthy cells and it is safe to use.
Here are some of the benefits of the Pao Pereira tree’s bark as an alternative medicine for health problems.
Pao Pereira extract to inhibit Pancreatic cancer cell
One of the major causes of death in the United States of America is Pancreatic Cancer because of the lack of early diagnosis of the disease. According to The American Cancer Society, Gemcitabine chemotherapy used as a primary treatment does not provide sufficient results in the advanced stage of pancreatic cancer and is not very effective to destroy cancer cells because of that the survival rate of patients in the advanced stage is only 5%. Cancer Stem-like Cells (CSC) are not affected much by this treatment and can survive which leads to the regeneration of new tumors. The self-renewal feature of the CSC causes the reappearance or regeneration of the tumor even after the chemotherapy.
Natural plant Pao Pereira has been used in the combination of other drugs for the treatment of many diseases all around the world for many years. The natural compound of PaoPereria possesses anticancer, anti-viral, antiplasmodial properties and is found to be effective in the prevention of tumor progression by inhibiting CSC. The use of Pao Pereira jointly with gemcitabine provides better outcomes by impeding or destroying cancer cells. The Pao Pereira is also very effective and used as alternative medicine in the case of prostate, ovarian cancer.
Prevent Ovarian Cancer Stem Cell Growth
It has also been found the use of the Pao Pereira extract in combination with Rauwolfiavomitoria is able to hinder the growth of cancer stem cells that causes ovarian cancer without having any side effects on healthy cells.
Treatment of Benign Prostatic Hyperplasia (BPH)
Pao Pereira extract is the most effective in the treatment of benign prostatic hyperplasia (BPH) which is common found in men older than 70-80 years of age. The healing compound (beta-carboline alkaloids) separated from the Pao is used to stop inflammation caused by NFκB signaling and thus defeat BPH in the urinary system of elder men.
Prostate Cancer in Men
Prostate cancer in men is caused by the population of androgen hormones and it resists androgen ablation therapy, which is used to treat prostate cancer, very easily. Androgen ablation therapy is used to decrease androgen hormones by the use of medicines or surgical treatment. Unfortunately, the consequences of Androgen Ablation Therapy did not show sufficient results and the survival rate is 30% in the case of distant prostate cancer. Pao Pereira extract which is made up of the bark of a Pao tree has got anti-cancer agents that have the ability to hinder the growth of androgen hormones and thus prevent the progression of prostate cancer cells.
Other Medicinal benefits of Pao Pereira
The medicinal property of the plant provided good results in HIV treatment by thwarting the accretion of viruses. Pao extract from the bark of the Pao tree is used to build up a strong immunity system, decontaminate the blood, and prevent microbes that cause penis, stomach, & liver infections.
Pao Pereira extract is beneficial in the treatment of various diseases and its anti-cancer property without any adverse effect permits it to be used for cancer treatment. Pao Pereira is believed to be effective against Epstein-Barr virus, Covid-19, HIV, herpes.