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IVF- All You Need To Know

admin by admin
November 10, 2020
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IVF- All You Need To Know
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In 1978, Louise Brown became the world’s first baby to change state by in vitro fertilization, or IVF.  Her birth revolutionized the field of reproductive medicine. As per the latest data, approximately  one in eight heterosexual couples has difficulty conceiving. Homosexual couples and single parents  often need clinical help to form a baby, the demand for IVF has been growing. IVF is so common,  that quite 5 million babies are born through this technology.

In this article specialists from Nisha IVF will discuss how IVF actually works. Nisha IVF is one of  the hospitals which provides the best IVF treatment in Ahmedabad. It is a leading hospital in  Ahmedabad offering holistic fertility care for the past five years with a well-trained and expert team  of gynecologists and fertility specialists. Specialists say that IVF works by mimicking the brilliant  design of sexual reproduction.

Natural Process of Baby Making

In order to know IVF, we first got to take a glance at the natural action of baby-making. Believe it  or not, it all starts in the brain. Roughly fifteen days before fertilization can happen, the anterior  pituitary gland secretes the follicle-stimulating hormone, FSH, which ripens a couple of follicles of  the ovary that then release estrogen. Each follicle contains one egg, and on average, just one follicle  becomes fully mature. As it grows and continues to release estrogen, this hormone helps coordinate  the growth and preparation of the uterus. It also communicates to the brain how well the follicle is  developing. When the estrogen level is high enough, the anterior pituitary gland releases a surge of  LH, which triggers ovulation and causes the follicle to rupture and release the egg. Once the egg  leaves the ovary, it’s directed into the Fallopian tube by the finger-like fimbriae. If the egg isn’t  fertilized by sperm within 24 hours, the unfertilized egg will die, and therefore the entire system  will reset itself, preparing to make a replacement egg and uterine lining the following month.

Fertilization Process

The egg is that the largest cell of the human body. It is protected by a thick, extracellular shell of  sugar and protein which is called the zona. The zona thwarts the entry and fusion of more than one  sperm, the littlest cell within the body. It takes a person two to 3 months to form sperm, and  therefore the process constantly renews. Each ejaculation during sexual activity releases quite 100  million sperm. But only 100 approximately will ultimately make it to the proximity of the egg, and  just one will successfully penetrate through the armor of the zona. Upon successful fertilization, the  zygote immediately starts developing into an embryo and takes approximately three days to succeed  in the uterus. There, it requires another three approximately days to implant firmly into the  endometrium, the inner lining of the uterus. Once implanted, the cells secrete a hormone that signals  to the ovulated follicle that there is a pregnancy in the uterus. This helps rescue that follicle, now  called the corpus luteum, from degenerating because it normally would neutralize that stage of the  cycle. The corpus luteum is liable for producing the progesterone, required to take care of the  pregnancy until six to seven weeks of gestation when the placenta develops and takes over until the  baby is born about 40 weeks later.

Now, How does one Make a Baby during a Lab?

In patients undergoing IVF, FSH is run at levels that are above present to cause controlled  overstimulation of the ovaries in order that they ultimately produce multiple eggs. The eggs are then  retrieved just before ovulation would occur, while the lady is under anesthesia, through an  aspirating needle that’s guided by ultrasound. In the laboratory, the identified eggs are stripped of  their surrounding cells and kept ready for fertilization in a Petri dish. Most sperm samples are  produced by masturbation.

Fertilization Process in IVF

Fertilization can occur by one of two techniques. In the first, the eggs are incubated with thousands  of sperm and fertilization occurs naturally over a few hours. The second technique maximizes the  certainty of fertilization as it uses a needle to place a single sperm precisely inside the egg. This  method is more useful when there is a problem with the quality of the sperm. After fertilization,  embryos are further screened for any genetic suitability. They are frozen for later attempted  pregnancies, or delivered into the woman’s uterus via a catheter. The common process is to transfer  the embryo three days after fertilization when the embryo has eight cells. It can be done on day five  also when the embryo is called a blastocyst and has hundreds of cells.

Things To Consider

If the woman’s eggs are of poor quality due to age or toxic exposures or have been removed due to  cancer, donor eggs should be used to avoid complications. In the case that the intended mother has a  problematic uterus, or lacks one, another woman can use her uterus to carry the pregnancy which is  known as surrogacy. To increase the chance of success, which is as high as 40% for a woman  younger than 35 years, doctors sometimes transfer multiple embryos at the same time. This is why  IVF results in twins and triplets more often compared to natural pregnancies. However, most clinics  seek to minimize the chances of multiple pregnancies, as they are riskier for mothers and babies.

Final Takeaway

Today millions of babies, like Louise Brown, have been born from IVF and are having normal,  healthy lives. So far, IVF seems safe for women. Because of the higher success rate, better genetic

testing delayed childbearing, increased accessibility, and diminishing cost, the day is not so far  when artificial baby-making via IVF and related techniques will outpace natural reproduction.

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